antimicrobial resistance, icu,minimum inhibitory concetration

Patients admitted to intensive care units (ICUs) are at a greater risk of hospital acquired infection than other hospitalised patients and are more likely to die of that infection as a result of a multitude of compounding factors. Patients admitted to ICU’s are usually critically ill and require frequent monitoring. Recent reports show that the rapidity of emergence of multiple antibioticresistant organisms in the ICU is not being reflected by the same rate of development of new antimicrobial agents. It is, therefore, conceivable that patients with serious infections will soon no longer be treatable with currently available antimicrobials. Strict management of antibiotic policies and surveillance programmes for multiple resistant organisms, together with infection control procedures, need to be implemented and continuously audited. This review considers the epidemiology of antimicrobial resistence in the ICU, their consequences and proposes strategies to minimize the risk of antimicrobial resistence

by mulyadi